Student Lead Research
Each summer, a highly qualified and determined student from Washington & Jefferson College is selected to become the Summer Research Intern at Pain Diagnostics and Interventional Care. Under the mentorship of Dr. Provenzano, these students have had the opportunity to learn the process of scientific writing, present at national medical conferences, and make a difference in the lives of chronic pain patients. Each summer intern has been able to walk away from the experience with at least one publication and the first-hand experience of pain management practice both in the clinical setting and in the operating room. Many of Dr. Provenzano’s research interns have proceeded on to medical school and continued to nurture their own interest in medical and basic science research.
We have been fortunate at PDIC to welcome such talented and dedicated students and look forward to continuing the internship program. Dr. Provenzano often says one of the most rewarding aspects of his career is imparting his interest of scientific research into the lives of the next generation of medical professionals.
During his undergraduate years, Dr. Provenzano did research in Pittsburgh, PA which catalyzed his appreciation for furthering our collective understanding of medical knowledge. As he continued his research endeavors through medical school, residency, fellowship, and in private practice, Dr. Provenzano felt inspired to share this opportunity with ambitious students. He is proud of the accomplishments of his mentees and looks forward to meeting countless new students in years to come.
Selection of articles:
https://www.dovepress.com/current-perspectives-on-neurostimulation-for-the-management-of-chronic-peer-reviewed-fulltext-article-JPR
https://www.painmedicine-casereports.com/current/pdf?article=NDcw&journal=28
https://www.neuromodulationjournal.org/article/S1094-7159(21)03352-3/fulltext
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402455/
https://rapm.bmj.com/content/46/6/469.long
https://rapm.bmj.com/content/early/2019/05/06/rapm-2019-100422.info
https://pubmed.ncbi.nlm.nih.gov/26490243/
https://pubmed.ncbi.nlm.nih.gov/23974866/
https://pubmed.ncbi.nlm.nih.gov/23388614/
Industry Funded Research
The research department at Pain Diagnostics and Interventional Care has flourished since its inception in 2017. With the help of our fantastic patients, we have been fortunate enough to take part in furthering the understanding and efficacy of complex treatment options such as spinal cord stimulation (SCS) and radiofrequency ablation (RFA). As a private practice in a region dominated by large healthcare systems, we are incredibly proud of our ability to contribute greatly to the field of Pain Management. We are honored to state that our research department contributes more to the field of Pain Management than any other healthcare system in our region. For the betterment of the lives of our patients, and the lives of others who may walk through the door of another practice, we are invariably on a mission to provide those in chronic pain with effective and research-driven solutions.
Selection of articles:
https://onlinelibrary.wiley.com/doi/10.1111/papr.13066
https://www.painphysicianjournal.com/linkout?issn=&vol=23&page=87
https://www.neuromodulationjournal.org/article/S1094-7159(21)00054-4/fulltext
Research and education are crucial components of the Pain Diagnostics and Interventional Care mission. To learn more about research opportunities including clinical trials, please contact our office and ask to speak with one of our research coordinators.
– David Provenzano, MD
Student Lead Research
Each summer, a highly qualified and determined student from Washington & Jefferson College is selected to become the Summer Research Intern at Pain Diagnostics and Interventional Care. Under the mentorship of Dr. Provenzano, these students have had the opportunity to learn the process of scientific writing, present at national medical conferences, and make a difference in the lives of chronic pain patients. Each summer intern has been able to walk away from the experience with at least one publication and the first-hand experience of pain management practice both in the clinical setting and in the operating room. Many of Dr. Provenzano’s research interns have proceeded on to medical school and continued to nurture their own interest in medical and basic science research.
We have been fortunate at PDIC to welcome such talented and dedicated students and look forward to continuing the internship program. Dr. Provenzano often says one of the most rewarding aspects of his career is imparting his interest of scientific research into the lives of the next generation of medical professionals.
During his undergraduate years, Dr. Provenzano did research in Pittsburgh, PA which catalyzed his appreciation for furthering our collective understanding of medical knowledge. As he continued his research endeavors through medical school, residency, fellowship, and in private practice, Dr. Provenzano felt inspired to share this opportunity with ambitious students. He is proud of the accomplishments of his mentees and looks forward to meeting countless new students in years to come.
Selection of articles:
https://www.dovepress.com/current-perspectives-on-neurostimulation-for-the-management-of-chronic-peer-reviewed-fulltext-article-JPR
https://www.painmedicine-casereports.com/current/pdf?article=NDcw&journal=28
https://www.neuromodulationjournal.org/article/S1094-7159(21)03352-3/fulltext
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402455/
https://rapm.bmj.com/content/46/6/469.long
https://rapm.bmj.com/content/early/2019/05/06/rapm-2019-100422.info
Industry Funded Research
The research department at Pain Diagnostics and Interventional Care has flourished since its inception in 2017. With the help of our fantastic patients, we have been fortunate enough to take part in furthering the understanding and efficacy of complex treatment options such as spinal cord stimulation (SCS) and radiofrequency ablation (RFA). As a private practice in a region dominated by large healthcare systems, we are incredibly proud of our ability to contribute greatly to the field of Pain Management. We are honored to state that our research department contributes more to the field of Pain Management than any other healthcare system in our region. For the betterment of the lives of our patients, and the lives of others who may walk through the door of another practice, we are invariably on a mission to provide those in chronic pain with effective and research-driven solutions.
Selection of articles:
https://onlinelibrary.wiley.com/doi/10.1111/papr.13066
https://www.painphysicianjournal.com/linkout?issn=&vol=23&page=87
https://www.neuromodulationjournal.org/article/S1094-7159(21)00054-4/fulltext
Research and education are crucial components of the Pain Diagnostics and Interventional Care mission. To learn more about research opportunities including clinical trials, please contact our office and ask to speak with one of our research coordinators.
– David Provenzano, MD
Radiofrequency (RF) Ablation Prospective Outcomes Study (RAPID)
Boston Scientific is conducting this study to compile real-world outcomes of commercially approved Boston Scientific radiofrequency (RF) ablation systems in the treatment of patients diagnosed with pain.
Enrollment for this study is open. Please contact us for further details.
Coolief Cooled Radiofrequency vs. Standard Radiofrequency to manage Chronic Facetogenic Low Back Pain
Avanos is conducting this study to compare the effectiveness of Coolief Radiofrequency (CRFA) to Standard Radiofrequency (SRFA) in the management of chronic lumbar facetogenic back pain.
To learn more about the Avanos study, click here.
Enrollment for this study is open. Please contact us for further details.
DTM-LE Spinal Cord Stimulation Study
Medtronic is conducting this study to evaluate the efficacy and energy use of a low energy DTM (DTM-LE) Spinal Cord Stimulation (SCS) therapy for pain relief.
To learn more about the Medtronic study, click here.
Enrollment for this study is closed.
SCS Research Study
Medtronic is conducting this study to characterize the effects of stimulation parameters on pain scores, specific to the indication associated with Spinal Cord Stimulation (SCS) implant, with different SCS parameters during follow-up periods.
To learn more about the Medtronic study, click here.
Enrollment for this study is closed.
Coolief Cooled Radiofrequency vs. Conventional Radiofrequency to manage OA Knee Pain
Avanos is conducting this study to assess the relative effectiveness of genicular nerve ablation with the COOLIEF* Cooled Radiofrequency probe to manage moderate to severe knee pain in patients with osteoarthritis (OA) of the knee when compared to radiofrequency ablation using a Standard Radiofrequency probe.
To learn more about the Avanos study, click here.
Enrollment for this study is closed.
Prospective Clinical Trial of Duty-Cycled Stimulation using the Senza Spinal Cord Stimulation (SCS) System
Nevro researchers are conducting this study to evaluate a type of stimulation programming called “Duty Cycling” in patients with an existing Nevro SenzaTM Spinal Cord Stimulation system. In Duty Cycling, the stimulation is cycled between brief states of ‘ON’ and ‘OFF’, which allows for a reduction in battery recharging time. Researchers are aiming to determine if Duty Cycling can reduce the amount of recharging time while continuing to deliver safe and effective pain relief.
To learn more about the study, click here.
Enrollment for this study is closed.
TARGET Study- Dorsal Root Ganglion (DRG) stimulation for the Treatment of Complex Regional Pain Syndrome (CRPS)
Abbott, formerly St. Jude Medical, is conducting a phase IV, post-market, clinical trial for DRG stimulation. The therapy is FDA approved for Complex Regional Pain Syndrome (CRPS), formerly known as Reflex Sympathetic Dystrophy (RSD).
The phase III clinical trial, known as the ACCURATE study, showed that DRG stimulation was effective in 93.3% of patients.
To learn more about the TARGET study click here.
Our site is one of only a few sites in the greater Pittsburgh area. Enrollment for this study is closed.
Vectors Post Market: A study to assess Pain Relief using Spinal Cord Stimulation
Medtronic is conducting a study to evaluate the efficacy of spinal cord stimulation (SCS) therapy for low back and leg pain relief using high dose (HD) stimulation parameters delivered to neural targets identified during current commercial trial stimulation procedures.
This is a prospective, single-arm, multi-center study.
To learn more about the Vectors study click here.
Enrollment for this study is closed.
Stimgenics Open-Label, Post Market Study (SGX-SCS-RCT)
Stimgenics is conducted an open-label, post market study to assess the efficacy of new programming parameters compared to standard programming parameters using Medtronic’s IntellisTM Spinal Cord Stimulator device for individuals with chronic, intractable low back and leg pain.
To learn more about the Stimgenics study, click here.
Enrollment for this study is closed.
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Dr. David Provenzano, a leading expert throughout the nation for treating patients who suffer daily from pain, uses advanced diagnostic techniques to assess the source of the pain and develop a comprehensive and safe treatment approach that can significantly reduce your pain.
