Osteoarthritis is a non-inflammatory degenerative joint disease. It is the most common joint disorder in the United States affecting over 30 million Americans.1 Normally, cartilage covers the end of each bone, providing a smooth surface for motion between bones as well as a cushion. Unfortunately, the cartilage breaks down in people who suffer from osteoarthritis, resulting in symptoms such as swelling, pain, stiffness, and decreased range of motion.
Osteoarthritis is the most common type of arthritis in the knee. The prevalence of symptomatic knee osteoarthritis in patients aged 45 and older has been estimated between: 5.9 and 13.5 percent in men and 7.2 and 18.7 percent in women.1 People who overuse their joints, including athletes, military members, and people with physically demanding jobs may be more susceptible to developing osteoarthritis as they age. There is currently no known cure for osteoarthritis. Knee osteoarthritis is often accompanied by comorbidities such as obesity (90%), hypertension (40%), depression (30%), and diabetes (15%).1 As the world’s population continues to age, it is estimated that degeneration joint disease disorders such as osteoarthritis will impact at least 130 million individuals around the globe by the year 2050.1