Research/Clinical Trials

Pain Diagnostics and Interventional Care advances the field of pain medicine through appropriate clinical and basic science research. Research and education are crucial components of the Pain Diagnostics and Interventional Care mission. To learn more about research opportunities including clinical trials, please contact our office and ask to speak with one of our research coordinators.

Coolief Cooled Radiofrequency vs. Conventional Radiofrequency to Manage OA Knee Pain

This study is being performed to assess the relative effectiveness of genicular nerve ablation with the COOLIEF* Cooled Radiofrequency probe to manage moderate to severe knee pain in patients with osteoarthritis (OA) of the knee when compared to radiofrequency ablation using a Standard Radiofrequency probe.

To learn more about the Avanos study, click here.

Enrollment for this study is open.

Prospective Clinical Trial of Duty-Cycled Stimulation Using the SenzaTM Spinal Cord Stimulation (SCS) System

Nevro researchers are conducting this study to evaluate a type of stimulation programming called “Duty Cycling” in patients with an existing Nevro SenzaTM Spinal Cord Stimulation system. In Duty Cycling, the stimulation is cycled between brief states of ‘ON’ and ‘OFF’, which allows for a reduction in battery recharging time. Researchers are aiming to determine if Duty Cycling can reduce the amount of recharging time while continuing to deliver safe and effective pain relief.

To learn more about the study, click here.

Enrollment for this study is open.

TARGET Study- Dorsal Root Ganglion (DRG) stimulation for the treatment of Complex Regional Pain Syndrome (CRPS)

Abbott, formerly St. Jude Medical, is conducting a phase IV, post-market, clinical trial for DRG stimulation. The therapy is FDA approved for Complex Regional Pain Syndrome (CRPS), formerly known as Reflex Sympathetic Dystrophy (RSD).

The phase III clinical trial, known as the ACCURATE study, showed that DRG stimulation was effective in 93.3% of patients.

To learn more about the TARGET study click here.

Our site is one of only a few sites in the greater Pittsburgh area. Enrollment for this study is closed.

Vectors Post Market: A Study to Assess Pain Relief Using Spinal Cord Stimulation

Medtronic is conducting a study to evaluate the efficacy of spinal cord stimulation (SCS) therapy for low back and leg pain relief using high dose (HD) stimulation parameters delivered to neural targets identified during current commercial trial stimulation procedures.

This is a prospective, single-arm, multi-center study.

To learn more about the Vectors study click here.

Enrollment for this study is closed.

Stimgenics Open-Label, Post Market Study (SGX-SCS-RCT)

Stimgenics is conducted an open-label, post market study to assess the efficacy of new programming parameters compared to standard programming parameters using Medtronic’s IntellisTM Spinal Cord Stimulator device for individuals with chronic, intractable low back and leg pain.

To learn more about the Stimgenics study, click here.

Enrollment for this study is closed.